Differential effects of regulatory T cells in the meninges and spinal cord of male and female mice with neuropathic pain

NT Fiore, BA Keating, Y Chen, SI Williams… - Cells, 2023 - mdpi.com
… In this study, we utilised intrathecal adoptive transfer of … mechanical allodynia only in male
mice, and inflammatory and … in the mouse brain, potentiating neurological recovery after an …

Gut microbiota influences neuropathic pain through modulating proinflammatory and anti-inflammatory T cells

W Ding, Z You, Q Chen, L Yang, J Doheny… - Anesthesia & …, 2021 - journals.lww.com
… , as demonstrated by dampened mechanical allodynia and … Adoptive transfer of these T cells
alleviated the severity of … on the innate immune system and adaptive immune system are not …

[HTML][HTML] Sex-specific B cell and anti-myelin autoantibody response after peripheral nerve injury

HJ Lee, AG Remacle, SK Hullugundi… - Frontiers in Cellular …, 2022 - frontiersin.org
… of sexual dimorphism in adaptive immune regulation of neuropathic pain is necessary to …
B cell and splenocyte adoptive transfer, which potentiate mechanical allodynia in males post…

The Antinociceptive Potential of Camellia japonica Leaf Extract, (−)-Epicatechin, and Rutin against Chronic Constriction Injury-Induced Neuropathic Pain in Rats

EY Lim, C Lee, YT Kim - Antioxidants, 2022 - mdpi.com
… of neuropathic pain involves the peripheral immune system … and further potentiate
neuropathic pain. Inflammatory … attenuated mechanical allodynia in neuropathic pain models […

Peripheral Beta-2 Adrenergic Receptors Mediate the Sympathetic Efferent Activation from Central Nervous System to Splenocytes in a Mouse Model of Fibromyalgia

S Yamashita, N Dozono, S Tobori, K Nagayasu… - International Journal of …, 2023 - mdpi.com
… Abnormalities in the peripheral immune system are involved in the pathophysiology of … of
neuropathic pain, the adoptive transfer of splenocytes derived from chronic constriction injury (…

The neuroimmunology of chronic pain: from rodents to humans

PM Grace, VL Tawfik, CI Svensson… - Journal of …, 2021 - Soc Neuroscience
… to pain (pain OR hyperalgesia OR allodynic OR allodynia OR … chronic pain after injury is
activation of the immune system. … neuropathic pain in preclinical models. For example, using a …

[HTML][HTML] Repetitive transcranial magnetic stimulation regulates neuroinflammation in neuropathic pain

YW Bai, QH Yang, PJ Chen, XQ Wang - Frontiers in Immunology, 2023 - frontiersin.org
… various immune cells near or within peripheral nerves. … IL-1β or lipopolysaccharide on
long-term potentiation (57–59)… and astrocytes, resulting in chronic allodynia development (71–76). …

Exploring the mechanism of immediate analgesic effect of 1-time tuina intervention in minor chronic constriction injury rats using RNA-seq

H Wang, Z Liu, T Yu, Y Zhang, Y Xu, Y Jiao… - Frontiers in …, 2022 - frontiersin.org
Neuropathic pain (NP) is a syndrome caused by injury or disease of the somatosensory nervous
system, either in the periphery … the model and tuina groups showed significant allodynia, …

… interleukin-10 gene therapy ameliorates neuropathic pain as measured by both classical static allodynia and a novel supra-spinally mediated pain assay, the Two …

MA Clements, AJ Kwilasz, ST Litwiler, Z Sents… - … , Behavior, and Immunity, 2023 - Elsevier
… across a prolonged timecourse, enabling the multi-week assessment of neuropathic pain
development after peripheral nerve injury as well as multi-week assessment of resolution of …

Immunotherapy and pain

J Zhao, A Roberts, Y Huh, RR Ji - Neuroimmune interactions in pain …, 2023 - Springer
… Furthermore, PD-1/PD-L1 signaling potentiates the TREK2 … the allodynia and pain
hypersensitivity from neuropathic pain. … cover the adoptive transfer of macrophages and T-cells for …